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Molecular Dynamics Study of the Role of the Spine of Hydration in DNA A-Tracts in Determining Nucleosome Occupancy

A-tracts in DNA are generally associated with reduced nucleosome occupancy relative to other sequences, such that the longer the A-tract, the less likely that nucleosomes are found. In this paper we use molecular dynamics methods to study the structural properties of A-tracts, and in particular the...

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Detalhes bibliográficos
Main Authors: Zhu, Xiao, Schatz, George C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508256/
https://ncbi.nlm.nih.gov/pubmed/23102092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp3084887
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