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Metabolic Function of a Suboptimal Transplanted Islet Mass in Nonhuman Primates on Rapamycin Monotherapy

Although islet transplantation may restore insulin independence to individuals with type 1 diabetes mellitus, most have abnormal glucose tolerance. We asked whether the defective glucose tolerance is due to inadequate β-cell mass or to impaired insulin sensitivity. We performed metabolic studies on...

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Detalhes bibliográficos
Main Authors: Soleimanpour, Scott A., Hirshberg, Boaz, Bunnell, David J., Sumner, Anne E., Ader, Marilyn, Remaley, Alan T., Rother, Kristina I., Rickels, Michael R., Harlan, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508173/
https://ncbi.nlm.nih.gov/pubmed/22080915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096368911X603620
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