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Spinal Cord Injury-Induced Osteoporosis: Pathogenesis and Emerging Therapies
Spinal cord injury causes rapid, severe osteoporosis with increased fracture risk. Mechanical unloading after paralysis results in increased osteocyte expression of sclerostin, suppressed bone formation, and indirect stimulation of bone resorption. At this time there are no clinical guidelines to pr...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3508135/ https://ncbi.nlm.nih.gov/pubmed/22983921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11914-012-0117-0 |
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