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Spinal Cord Injury-Induced Osteoporosis: Pathogenesis and Emerging Therapies

Spinal cord injury causes rapid, severe osteoporosis with increased fracture risk. Mechanical unloading after paralysis results in increased osteocyte expression of sclerostin, suppressed bone formation, and indirect stimulation of bone resorption. At this time there are no clinical guidelines to pr...

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Sonraí Bibleagrafaíochta
Main Authors: Battaglino, Ricardo A., Lazzari, Antonio A., Garshick, Eric, Morse, Leslie R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508135/
https://ncbi.nlm.nih.gov/pubmed/22983921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11914-012-0117-0
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