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Euchromatin islands in large heterochromatin domains are enriched for CTCF binding and differentially DNA-methylated regions

BACKGROUND: The organization of higher order chromatin is an emerging epigenetic mechanism for understanding development and disease. We and others have previously observed dynamic changes during differentiation and oncogenesis in large heterochromatin domains such as Large Organized Chromatin K (ly...

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Bibliografiske detaljer
Main Authors: Wen, Bo, Wu, Hao, Loh, Yuin-Han, Briem, Eirikur, Daley, George Q, Feinberg, Andrew P
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507770/
https://ncbi.nlm.nih.gov/pubmed/23102236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-566
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