DNA methylation of the IGF2/H19 imprinting control region and adiposity distribution in young adults

BACKGROUND: The insulin-like growth factor 2 (IGF2) and H19 imprinted genes control growth and body composition. Adverse in-utero environments have been associated with obesity-related diseases and linked with altered DNA methylation at the IGF2/H19 locus. Postnatally, methylation at the IGF2/H19 im...

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Autori principali: Huang, Rae-Chi, Galati, John C, Burrows, Sally, Beilin, Lawrence J, Li, Xin, Pennell, Craig E, van Eekelen, JAM, Mori, Trevor A, Adams, Leon A, Craig, Jeffrey M
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507742/
https://ncbi.nlm.nih.gov/pubmed/23148549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-4-21
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