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Origin of the Conformational Heterogeneity of Cardiolipin-bound Cytochrome c

Interactions of cytochrome c (cyt c) with cardiolipin (CL) partially unfold the protein activating its peroxidase function, a critical event in the execution of apoptosis. However, structural features of the altered protein species in the heterogeneous ensemble are difficult to probe with ensemble a...

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Detalles Bibliográficos
Main Authors: Hong, Yuning, Muenzner, Julia, Grimm, Sebastian K., Pletneva, Ekaterina V.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507619/
https://ncbi.nlm.nih.gov/pubmed/23066867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja307426k
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