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Metformin and the Risk of Cancer: Time-related biases in observational studies
OBJECTIVE: Time-related biases in observational studies of drug effects have been described extensively in different therapeutic areas but less so in diabetes. Immortal time bias, time-window bias, and time-lag bias all tend to greatly exaggerate the benefits observed with a drug. RESEARCH DESIGN AN...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Diabetes Association
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3507580/ https://ncbi.nlm.nih.gov/pubmed/23173135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc12-0788 |
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