Metabolism of Insulin Glargine After Repeated Daily Subcutaneous Injections in Subjects With Type 2 Diabetes

OBJECTIVE: To investigate concentration of plasma insulin glargine after its subcutaneous dosing compared with concentration of its metabolites 1 (M1) and 2 (M2) in subjects with type 2 diabetes. RESEARCH DESIGN AND METHODS: Nine subjects underwent a 32-h euglycemic glucose clamp study (0.4 units/kg...

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Autori principali: Lucidi, Paola, Porcellati, Francesca, Rossetti, Paolo, Candeloro, Paola, Andreoli, Anna Marinelli, Cioli, Patrizia, Hahn, Annke, Schmidt, Ronald, Bolli, Geremia B., Fanelli, Carmine G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2012
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507576/
https://ncbi.nlm.nih.gov/pubmed/23086139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc12-0271
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