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Increased Bacterial Translocation in Gluten-Sensitive Mice Is Independent of Small Intestinal Paracellular Permeability Defect

AIM: We investigated whether treatment with gliadin induces a paracellular permeability defect that enhances bacterial translocation to mesenteric lymph nodes (MLN) via resident dendritic cells (DC) expressing TLR-2 or 4 in HCD4/HLA-DQ8 transgenic mice. METHODS: HLA-DQ8 transgenic mice were sensitiz...

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Detalhes bibliográficos
Main Authors: Silva, Manuel A., Jury, Jennifer, Sanz, Yolanda, Wiepjes, Michelle, Huang, Xianxi, Murray, Joseph A., David, Chella S., Fasano, Alessio, Verdú, Elena F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507358/
https://ncbi.nlm.nih.gov/pubmed/21822909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10620-011-1847-z
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