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Foxa2 mediates critical functions of prechordal plate in patterning and morphogenesis and is cell autonomously required for early ventral endoderm morphogenesis

Axial mesendoderm is comprised of prechordal plate and notochord. Lack of a suitable Cre driver has hampered the ability to genetically dissect the requirement for each of these components, or genes expressed within them, to anterior patterning. Here, we have utilized Isl1-Cre to investigate roles o...

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Detalhes bibliográficos
Main Authors: Harrelson, Zachary, Kaestner, Klaus H., Evans, Sylvia M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507292/
https://ncbi.nlm.nih.gov/pubmed/23213408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.2012040
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