Taperin (c9orf75), a mutated gene in nonsyndromic deafness, encodes a vertebrate specific, nuclear localized protein phosphatase one alpha (PP1α) docking protein

The promiscuous activity of protein phosphatase one (PP1) is controlled in the cell by associated proteins termed regulatory or targeting subunits. Using biochemical and proteomic approaches we demonstrate that the autosomal recessive nonsyndromic hearing loss gene, taperin (C9orf75), encodes a prot...

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Detalhes bibliográficos
Main Authors: Ferrar, Tony, Chamousset, Delphine, De Wever, Veerle, Nimick, Mhairi, Andersen, Jens, Trinkle-Mulcahy, Laura, Moorhead, Greg B. G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507197/
https://ncbi.nlm.nih.gov/pubmed/23213405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.2011049
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