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Phenotypic differences between apolipoprotein E genetic subgroups: research and clinical implications

With the recent interest in Alzheimer's disease course modification and earlier, even preclinical, intervention, questions have arisen regarding the potentially confounding impact of apolipoprotein E (APOE) genotype on study design, therapeutic outcomes, and even clinical practice. APOE e4 carr...

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Detalhes bibliográficos
Autor principal: Caselli, Richard J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3506934/
https://ncbi.nlm.nih.gov/pubmed/22694803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt123
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