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Potential therapeutic approaches for modulating expression and accumulation of defective lamin A in laminopathies and age-related diseases

Scientific understanding of the genetic components of aging has increased in recent years, with several genes being identified as playing roles in the aging process and, potentially, longevity. In particular, genes encoding components of the nuclear lamina in eukaryotes have been increasingly well c...

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Detalhes bibliográficos
Main Authors: Zhavoronkov, Alex, Smit-McBride, Zeljka, Guinan, Kieran J., Litovchenko, Maria, Moskalev, Alexey
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3506837/
https://ncbi.nlm.nih.gov/pubmed/23090008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-012-0962-4
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