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Lipid peroxyl radicals mediate tyrosine dimerization and nitration in membranes

Protein tyrosine dimerization and nitration by biologically-relevant oxidants usually depend on the intermediate formation of tyrosyl radical (•Tyr). In the case of tyrosine oxidation in proteins associated to hydrophobic biocompartments, the participation of unsaturated fatty acids in the process m...

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Detalhes bibliográficos
Main Authors: Bartesaghi, Silvina, Wenzel, Jorge, Trujillo, Madia, López, Marcos, Joseph, Joy, Kalyanaraman, Balaraman, Radi, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3506709/
https://ncbi.nlm.nih.gov/pubmed/20170094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx900446r
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