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Signature-tagging of a bacterial isolate demonstrates phenotypic variability of the progeny in vivo in the absence of defined mutations
Awareness of the high degree of redundancy that occurs in several nutrient uptake pathways of H. influenzae led us to attempt to develop a quantitative STM method that could identify both null mutants and mutants with decreased fitness that remain viable in vivo. To accomplish this task we designed...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3506178/ https://ncbi.nlm.nih.gov/pubmed/23085534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mimet.2012.10.005 |
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