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A Case of Adult-Onset Alexander Disease Featuring Severe Atrophy of the Medulla Oblongata and Upper Cervical Cord on Magnetic Resonance Imaging

Adult-onset Alexander disease (AOAD) has been increasingly recognized since the identification of the glial fibrillary acidic protein gene mutation in 2001. We report on a 56-year-old man who was genetically confirmed as AOAD with the glial fibrillary acidic protein mutation of p.M74T. He developed...

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Autors principals: Yonezu, Tadahiro, Ito, Shoichi, Kanai, Kazuaki, Masuda, Saeko, Shibuya, Kazumoto, Kuwabara, Satoshi
Format: Artigo
Idioma:Inglês
Publicat: S. Karger AG 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3506048/
https://ncbi.nlm.nih.gov/pubmed/23185175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000345303
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