Topoisomerase II α Status in Renal Medullary Carcinoma: Immuno-Expression and Gene Copy Alterations of a Potential Target of Therapy

PURPOSE: Renal medullary carcinoma is an aggressive renal neoplasm without currently available effective therapy to our knowledge. Topoisomerase II α is a gyrase involved in cell proliferation, and DNA maintenance and repair. Topoisomerase II α is a target of inhibiting agents such as anthracyclines...

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Detalhes bibliográficos
Main Authors: Albadine, Roula, Wang, Wenle, Brownlee, Noel A., Toubaji, Antoun, Billis, Athanase, Argani, Perdram, Epstein, Jonathan I., Garvin, A. Julian, Cousi, Rima, Schaeffer, Edward M., Pavlovich, Christian, Netto, George J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505671/
https://ncbi.nlm.nih.gov/pubmed/19539329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.juro.2009.03.078
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