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On the Meaning of Affinity Limits in B-Cell Epitope Prediction for Antipeptide Antibody-Mediated Immunity

B-cell epitope prediction aims to aid the design of peptide-based immunogens (e.g., vaccines) for eliciting antipeptide antibodies that protect against disease, but such antibodies fail to confer protection and even promote disease if they bind with low affinity. Hence, the Immune Epitope Database (...

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Detalhes bibliográficos
Autor principal: Caoili, Salvador Eugenio C.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505629/
https://ncbi.nlm.nih.gov/pubmed/23209458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/346765
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