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A TRPC6-dependent pathway for myofibroblast transdifferentiation and wound healing in vivo
After injury or cytokine stimulation, fibroblasts transdifferentiate into myofibroblasts, contractile cells that secrete extracellular matrix for wound healing and tissue remodeling. Here, a genome-wide screen identified TRPC6, a Ca(2+) channel necessary and sufficient for myofibroblast transformati...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3505601/ https://ncbi.nlm.nih.gov/pubmed/23022034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.08.017 |
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