Plasma leptin and neuropeptide Y concentrations in patients with rheumatoid arthritis treated with infliximab, a TNF-α antagonist

TNF-α is one of the key proinflammatory cytokines in pathogenesis of rheumatoid arthritis (RA). TNF-α was also found to enhance synthesis of leptin. Leptin is mainly adipocyte-derived hormone controlling appetite and energy expenditure. It acts through inhibition of neuropeptide Y secretion. It is p...

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Bibliografiske detaljer
Main Authors: Kopec-Medrek, Magdalena, Kotulska, Anna, Widuchowska, Malgorzata, Adamczak, Marcin, Więcek, Andrzej, Kucharz, Eugene J.
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2011
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505553/
https://ncbi.nlm.nih.gov/pubmed/22048440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00296-011-2182-6
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