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Replication Protein A (RPA) Phosphorylation Prevents RPA Association with Replication Centers

Mammalian replication protein A (RPA) undergoes DNA damage-dependent phosphorylation at numerous sites on the N terminus of the RPA2 subunit. To understand the functional significance of RPA phosphorylation, we expressed RPA2 variants in which the phosphorylation sites were converted to aspartate (R...

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Autori principali: Vassin, Vitaly M., Wold, Marc S., Borowiec, James A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC350552/
https://ncbi.nlm.nih.gov/pubmed/14966274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.5.1930-1943.2004
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