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Generation of animals allowing the conditional inactivation of the Pax4 gene
Pax4 belongs to the paired-box family of transcription factors. The analysis of loss- and gain-of-function mutant animals revealed that this factor plays a crucial role in the endocrine pancreas. Indeed, Pax4 is required for the genesis of insulin-producing beta-cells. Remarkably, the sole misexpres...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Springer Netherlands
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3505494/ https://ncbi.nlm.nih.gov/pubmed/22717987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11248-012-9624-0 |
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