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Intracellular injection of t he catalytic subunit of cyclic AMP-dependent protein kinase simulates facilitation of transmitter release underlying behavioral sensitization in Aplysia.

It has been difficult to establish whether cyclic AMP-mediated protein phosphorylation in nerve cells plays a specific role in synaptic transmission. This difficulty can be overcome in higher invertebrates because their large neurons allow the injection of protein molecules into the cell. We have us...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Castellucci, V F, Kandel, E R, Schwartz, J H, Wilson, F D, Nairn, A C, Greengard, P
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350531/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6111794/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.12.7492
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