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COMBINATION TREATMENT OF STROKE WITH SUB-THERAPEUTIC DOSES OF SIMVASTATIN AND HUMAN UMBILICAL CORD BLOOD CELLS ENHANCES VASCULAR REMODELING AND IMPROVES FUNCTIONAL OUTCOME

Human umbilical cord blood cells (HUCBCs) have been employed as a restorative treatment for experimental stroke. In this study, we investigated whether transplantation of sub-therapeutic doses of HUCBCs and Simvastatin enhances cerebral vascular remodeling after stroke. Adult male Wistar rats (n=34)...

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Detalhes bibliográficos
Main Authors: Cui, X., Chopp, M., Zacharek, A., Dai, J., Zhang, C., Yan, T., Ning, R., Roberts, C., Shehadah, A., Kuzmin-Nichols, N., Sanberg, C. Davis, Chen, J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505259/
https://ncbi.nlm.nih.gov/pubmed/23041512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2012.09.066
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