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Sample Size Calculation for the Proportional Hazards Cure Model

In clinical trials with time-to-event endpoints, it is not uncommon to see a significant proportion of patients being cured (or long-term survivors), such as trials for the non-Hodgkins lymphoma disease. The popularly used sample size formula derived under the proportional hazards (PH) model may not...

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Bibliographic Details
Main Authors: Wang, Songfeng, Zhang, Jiajia, Lu, Wenbin
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505258/
https://ncbi.nlm.nih.gov/pubmed/22786805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.5465
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