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Expression and Function of APP and its Metabolites Outside the Central Nervous System

Amyloid precursor protein (APP) derived amyloid beta (Aβ) peptides have been extensively investigated in Alzheimer’s disease pathology of the brain. However, the function of full length APP in the central nervous system remains unclear. Even less is known about the function of this ubiquitously expr...

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Detalhes bibliográficos
Main Authors: Puig, Kendra L., Combs, Colin K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505247/
https://ncbi.nlm.nih.gov/pubmed/22846461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2012.07.009
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