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Lipid fluidity markedly modulates the binding of serotonin to mouse brain membranes.

The binding of [3H]serotonin to mouse brain crude membrane and synaptosomal membrane preparations was investigated as a function of membrane fluidity changes by lipids. The microviscosity (eta) of the synaptic membranes was increased by in vitro incubation with either cholesteryl hemisuccinate or st...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Heron, D S, Shinitzky, M, Hershkowitz, M, Samuel, D
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1980
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350524/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6938985/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.12.7463
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