SYNTHESIS OF SYMMETRICAL METHYLENEBIS(ALKYL HYDROGEN PHOSPHONATES) BY SELECTIVE CLEAVAGE OF METHYLENEBIS(DIALKYL PHOSPHONATES) WITH MORPHOLINE

The preparation of partial esters of methylenebisphosphonic acids has been of recent interest due to their potential therapeutic applications. This paper describes a convenient method to prepare symmetrical methylenebis(alkyl hydrogen phosphonates) by the selective cleavage of the corresponding meth...

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Päätekijät: Reddy, Gantla Vidyasagar, Jacobs, Hollie K., Gopalan, Aravamudan S., Barrans, Richard E., Dietz, Mark L., Stepinski, Dominique C., Herlinger, Albert W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505106/
https://ncbi.nlm.nih.gov/pubmed/23180889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1081/SCC-120027271
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