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Design and synthesis of boron containing potential pan-RAR inverse agonists
We designed and successfully synthesized the compounds 5 and 8 as potential pan-RAR (retinoic acid receptor) agonists. These two compounds were designed based on an existing pan-RAR agonist (BMS493). We synthesized compound 5, in which the carboxylic acid group in BMS 493 was replaced by boronic est...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3505081/ https://ncbi.nlm.nih.gov/pubmed/23180890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2011.12.118 |
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