Genetic Diversity and Naturally Polymorphisms in HIV Type 1 Integrase Isolates from Maputo, Mozambique: Implications for Integrase Inhibitors

HIV proviral DNA integration into the host chromosome is carried out by integrase becoming an important target antiretroviral therapy. Raltegravir was the first integrase inhibitor approved for use in HIV therapy and elvitegravir is in the late phase of clinical development; both show good results i...

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Dettagli Bibliografici
Autori principali: Oliveira, Michelli F., Ramalho, Dulce B., Abreu, Celina M., Vubil, Adolfo, Mabunda, Nédio, Ismael, Nalia, Francisco, Cidia, Jani, Ilesh V., Tanuri, Amilcar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2012
Soggetti:
Sequence Notes
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505052/
https://ncbi.nlm.nih.gov/pubmed/22497664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2012.0058
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