Genetic Diversity and Naturally Polymorphisms in HIV Type 1 Integrase Isolates from Maputo, Mozambique: Implications for Integrase Inhibitors

HIV proviral DNA integration into the host chromosome is carried out by integrase becoming an important target antiretroviral therapy. Raltegravir was the first integrase inhibitor approved for use in HIV therapy and elvitegravir is in the late phase of clinical development; both show good results i...

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Detalhes bibliográficos
Main Authors: Oliveira, Michelli F., Ramalho, Dulce B., Abreu, Celina M., Vubil, Adolfo, Mabunda, Nédio, Ismael, Nalia, Francisco, Cidia, Jani, Ilesh V., Tanuri, Amilcar
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
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Sequence Notes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505052/
https://ncbi.nlm.nih.gov/pubmed/22497664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2012.0058
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