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Homeobox Protein HB9 Binds to the Prostaglandin E Receptor 2 Promoter and Inhibits Intracellular cAMP Mobilization in Leukemic Cells

The transcription factor HB9, encoded by the homeobox gene B9 (HLXB9), is involved in the development of pancreatic beta- and motor neuronal cells. In addition, HLXB9 is recurrently rearranged in young children with acute myeloid leukemia characterized by a chromosomal translocation t(7;12)-HLXB9/TE...

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Detalhes bibliográficos
Main Authors: Wildenhain, Sarah, Ingenhag, Deborah, Ruckert, Christian, Degistirici, Özer, Dugas, Martin, Meisel, Roland, Hauer, Julia, Borkhardt, Arndt
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504783/
https://ncbi.nlm.nih.gov/pubmed/23048027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.308965
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