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Notch3 and Mef2c Proteins Are Mutually Antagonistic via Mkp1 Protein and miR-1/206 MicroRNAs in Differentiating Myoblasts

The Notch signaling pathway is a well known regulator of skeletal muscle stem cells known as satellite cells. Loss of Notch1 signaling leads to spontaneous myogenic differentiation. Notch1, normally expressed in satellite cells, is targeted for proteasomal degradation by Numb during differentiation....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gagan, Jeffrey, Dey, Bijan K., Layer, Ryan, Yan, Zhen, Dutta, Anindya
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504751/
https://ncbi.nlm.nih.gov/pubmed/23055528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.378414
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