Inhibition of DNA Damage-induced Apoptosis through Cdc7-mediated Stabilization of Tob

Cells respond to DNA damage by activating alternate signaling pathways that induce proliferation arrest or apoptosis. The correct balance between these two pathways is important for maintaining genomic integrity and preventing unnecessary cell death. The mechanism by which DNA-damaged cells escape f...

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Detalhes bibliográficos
Main Authors: Suzuki, Toru, Tsuzuku, Junko, Hayashi, Akiyo, Shiomi, Yasushi, Iwanari, Hiroko, Mochizuki, Yasuhiro, Hamakubo, Takao, Kodama, Tatsuhiko, Nishitani, Hideo, Masai, Hisao, Yamamoto, Tadashi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504742/
https://ncbi.nlm.nih.gov/pubmed/23066029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.353805
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