Apoptosis-like programmed cell death induces antisense ribosomal RNA (rRNA) fragmentation and rRNA degradation in Leishmania

Few natural antisense (as) RNAs have been reported as yet in the unicellular protozoan Leishmania. Here, we describe that Leishmania produces natural asRNAs complementary to all ribosomal RNA (rRNA) species. Interestingly, we show that drug-induced apoptosis-like programmed cell death triggers fragm...

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Detalhes bibliográficos
Main Authors: Padmanabhan, P K, Samant, M, Cloutier, S, Simard, M J, Papadopoulou, B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504711/
https://ncbi.nlm.nih.gov/pubmed/22767185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.85
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