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Apoptotic Cells, at All Stages of the Death Process, Trigger Characteristic Signaling Events That Are Divergent from and Dominant over Those Triggered by Necrotic Cells: IMPLICATIONS FOR THE DELAYED CLEARANCE MODEL OF AUTOIMMUNITY(,)

Current models of autoimmunity suggest that delayed clearance of apoptotic cells leads to the presentation of apoptotic antigens in the context of inflammatory signals, with resultant autoimmunity. These models implicitly assume that, in contrast to early apoptotic cells (that retain membrane integr...

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Detalhes bibliográficos
Main Authors: Patel, Vimal A., Longacre, Angelika, Hsiao, Kevin, Fan, Hanli, Meng, Fanyong, Mitchell, Justin E., Rauch, Joyce, Ucker, David S., Levine, Jerrold S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504611/
https://ncbi.nlm.nih.gov/pubmed/16377620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M508342200
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