Phosphorylated oligosaccharides in lysosomal enzymes: identification of alpha-N-acetylglucosamine(1)phospho(6)mannose diester groups.

In human fibroblasts, the recognition of lysosomal enzymes by cell surface receptors is mediated by mannose 6-phosphate residues located on oligosaccharides that can be cleaved by endo-beta-N-acetylglucosaminidase H. About half of these oligosaccharides, as isolated from beta-hexosaminidase and cath...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Hasilik, A, Klein, U, Waheed, A, Strecker, G, von Figura, K
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1980
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350443/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6938953/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.12.7074
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