Gamma-Tocopherol Nebulization Decreases Oxidative Stress, Arginase Activity, and Collagen Deposition after Burn and Smoke Inhalation in the Ovine Model

More than 20,000 burn injury victims suffer from smoke inhalation injury in the United States annually. In an ovine model of acute lung injury, gamma-tocopherol (g-T) had a beneficial effect when nebulized into the airway. We hypothesize that g-T scavenges reactive oxygen and nitrogen species (ROS/R...

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Auteurs principaux: Yamamoto, Yusuke, Sousse, Linda E., Enkhbaatar, Perenlei, Kraft, Edward R., Deyo, Donald J., Wright, Charlotte L., Taylor, Alan, Traber, Maret G., Cox, Robert A., Hawkins, Hal K., Rehberg, Sebastian W., Traber, Lillian D., Herndon, David N., Traber, Daniel L.
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504354/
https://ncbi.nlm.nih.gov/pubmed/23160521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e3182758759
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