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Maternal obesity alters feto-placental Cytochrome P4501A1 activity

Cytochrome P4501A1 (CYP1A1), an important drug metabolizing enzyme, is expressed in human placenta throughout gestation as well as in fetal liver. Obesity, a chronic inflammatory condition, is known to alter CYP enzyme expression in non-placental tissues. In the present study, we test the hypothesis...

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Autori principali: DuBois, Barent N., O’Tierney, Perrie, Pearson, Jacob, Friedman, Jacob E., Thornburg, Kent, Cherala, Ganesh
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504187/
https://ncbi.nlm.nih.gov/pubmed/23046808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.placenta.2012.09.008
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