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Local complement-targeted intervention in periodontitis: proof-of-concept using a C5a receptor (CD88) antagonist()
When excessively activated or deregulated, complement becomes a major link between infection and inflammatory pathology including periodontitis. This oral inflammatory disease is associated with a dysbiotic microbiota, leads to the destruction of bone and other tooth-supporting structures, and exert...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3504137/ https://ncbi.nlm.nih.gov/pubmed/23089394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202339 |
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