The role of ATM and 53BP1 as predictive markers in cervical cancer

Treatment of advanced-stage cervical cancers with (chemo)radiation causes cytotoxicity through induction of high levels of DNA damage. Tumour cells respond to DNA damage by activation of the ‘DNA damage response’ (DDR), which induces DNA repair and may counteract chemoradiation efficacy. Here, we in...

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Bibliografski detalji
Glavni autori: Roossink, Frank, Wieringa, Hylke W, Noordhuis, Maartje G, ten Hoor, Klaske A, Kok, Mirjam, Slagter-Menkema, Lorian, Hollema, Harry, de Bock, Geertruida H, Pras, Elisabeth, de Vries, Elisabeth GE, de Jong, Steven, van der Zee, Ate GJ, Schuuring, Ed, Wisman, G Bea A, van Vugt, Marcel ATM
Format: Artigo
Jezik:Inglês
Izdano: Wiley Subscription Services, Inc., A Wiley Company 2012
Teme:
Cancer Cell Biology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504092/
https://ncbi.nlm.nih.gov/pubmed/22323184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.27488
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