Inside the Mind of a Medicinal Chemist: The Role of Human Bias in Compound Prioritization during Drug Discovery

Medicinal chemists’ “intuition” is critical for success in modern drug discovery. Early in the discovery process, chemists select a subset of compounds for further research, often from many viable candidates. These decisions determine the success of a discovery campaign, and ultimately what kind of...

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Detaylı Bibliyografya
Asıl Yazarlar: Kutchukian, Peter S., Vasilyeva, Nadya Y., Xu, Jordan, Lindvall, Mika K., Dillon, Michael P., Glick, Meir, Coley, John D., Brooijmans, Natasja
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504051/
https://ncbi.nlm.nih.gov/pubmed/23185259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048476
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