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Association of Germline Variation in CCNE1 and CDK2 with Breast Cancer Risk, Progression and Survival among Chinese Han Women

BACKGROUND: Somatic alterations of cyclin-dependent kinase 2 (CDK2)-cyclin E complex have been shown to contribute to breast cancer (BC) development and progression. This study aimed to explore the effects of single nucleotide polymorphisms (SNPs) in CDK2 and CCNE1 (a gene encoding G1/S specific cyc...

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Detalhes bibliográficos
Main Authors: Han, Ji-Yuan, Wang, Hui, Xie, Yun-Tao, Li, Yan, Zheng, Li-Yuan, Ruan, Yuan, Song, Ai-Ping, Tian, Xin-Xia, Fang, Wei-Gang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504019/
https://ncbi.nlm.nih.gov/pubmed/23185313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049296
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