Deoxycytidine kinase-mediated toxicity of deoxyadenosine analogs toward malignant human lymphoblasts in vitro and toward murine L1210 leukemia in vivo.

An inherited deficiency of adenosine deaminase (adenosine aminohydrolase, EC 3.5.4.4) produces selective lymphopenia and immunodeficiency disease in humans. Previous experiments have suggested that lymphospecific toxicity in this condition might result from the selective accumulation of toxic deoxya...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Carson, D A, Wasson, D B, Kaye, J, Ullman, B, Martin, D W, Robins, R K, Montgomery, J A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1980
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350391/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6256765/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.11.6865
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