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Functional role of post-translational modifications of Sp1 in tumorigenesis

Specific protein 1 (Sp1), the first transcription factor to be isolated, regulates the expression of numerous genes involved in cell proliferation, apoptosis, and differentiation. Recent studies found that an increase in Sp1 transcriptional activity is associated with the tumorigenesis. Moreover, po...

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Detalhes bibliográficos
Main Authors: Chang, Wen-Chang, Hung, Jan-Jong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503885/
https://ncbi.nlm.nih.gov/pubmed/23148884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-19-94
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