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Establishment of a conditional transgenic mouse model expressing human uncoupling protein 2 in vascular smooth muscle cells

Increased oxidative stress is involved in the development of vascular dysfunction and remodeling. Uncoupling protein 2 (UCP2) regulates the production of reactive oxygen species in vascular smooth muscle cells (SMCs). To promote the study of the role of UCP2 in vascular diseases, a transgenic mouse...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MA, SHUANGTAO, LI, DE, YANG, DACHUN, TAN, YAN, TANG, BING, JIN, FEIPENG, JIANG, SIHUA, LI, XIUCHUAN, YANG, YONGJIAN
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503749/
https://ncbi.nlm.nih.gov/pubmed/23181133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2012.620
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