Evolutionary approach to the question of immunoglobulin heavy chain switching: evidence from cloned human and mouse genes.
We have used cloned mouse and human heavy chain genes to identify regions of conserved homology between mouse and man and between mu and alpha genes. Using heteroduplex mapping, we find that coding segments for homologous domains appear to have been well conserved between the two species, but the sh...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1980
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350363/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6779282/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.11.6734 |
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