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Knockdown of hypoxia-inducible factor-1α accelerates peritoneal dissemination via the upregulation of MMP-1 expression in gastric cancer cell lines

This study was performed to clarify the role of hypoxia-inducible factor-1 α (HIF-1α) in the development of peritoneal dissemination in a xenograft mouse model of gastric cancer. HIF-1α knockdown (KD) and control (SC) gastric cancer cells, which were established using the MKN45 and MKN74 cell lines,...

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Sonraí Bibleagrafaíochta
Main Authors: HIRAKI, MASATSUGU, KITAJIMA, YOSHIHIKO, KAI, KEITA, NAKAMURA, JUN, HASHIGUCHI, KAZUYOSHI, NOSHIRO, HIROKAZU, MIYAZAKI, KOHJI
Formáid: Artigo
Teanga:Inglês
Foilsithe: D.A. Spandidos 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503539/
https://ncbi.nlm.nih.gov/pubmed/23181099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2012.600
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