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Improvement of Sensitivity to Tamoxifen in ER-Positive and Herceptin-Resistant Breast Cancer Cells

Her2 overexpression in ER-positive breast cancer cells such as BT474 (BT) cells has been found to confer resistance to tamoxifen, and suppression of Her2 improves the antiproliferative effects of tamoxifen. In this study, the responsiveness to tamoxifen in BT/HerR, Herceptin-resistant BT cell lines...

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Detalhes bibliográficos
Main Authors: Chen, Bin, Wang, Yuanzhong, Kane, Susan E., Chen, Shiuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503452/
https://ncbi.nlm.nih.gov/pubmed/18768663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JME-08-0026
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