Disruption of Abi1/Hssh3bp1 expression induces prostatic intraepithelial neoplasia in the conditional Abi1/Hssh3bp1 KO mice

Prostate cancer is one of the leading causes of cancer-related deaths in the United States and a leading diagnosed non-skin cancer in American men. Genetic mutations underlying prostate tumorigenesis include alterations of tumor suppressor genes. We tested the tumor suppressor hypothesis for ABI1/hS...

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Main Authors: Xiong, X, Chorzalska, A, Dubielecka, P M, White, J R, Vedvyas, Y, Hedvat, C V, Haimovitz-Friedman, A, Koutcher, J A, Reimand, J, Bader, G D, Sawicki, J A, Kotula, L
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503296/
https://ncbi.nlm.nih.gov/pubmed/23552839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2012.28
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