Exploitation of chick embryo environments to reprogram MYCN-amplified neuroblastoma cells to a benign phenotype, lacking detectable MYCN expression

Neuroblastoma is a paediatric cancer that arises from the sympathetic ganglia (SG) or adrenal gland. Tumours that occur in patients under 18 months of age have a particularly good prognosis and frequently undergo spontaneous regression. This led to the hypothesis that developmental cues in the young...

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Detalhes bibliográficos
Main Authors: Carter, R, Mullassery, D, See, V, Theocharatos, S, Pizer, B, Losty, P D, Jesudason, E, Moss, D J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503288/
https://ncbi.nlm.nih.gov/pubmed/23552815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2012.24
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